Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis

Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB leading cause of death globally, accounting for approximately 1.5 million deaths per year. The aim this article was to evaluate immunological role Interleukin (IL) 18 and 22 in patients infected with MTB multi-drug resistant MDRTB. A total 182 individuals suspected admitted center AL-Najaf City, Iraq. sputum acid-fast stain performed each individual GeneXpert® heminested real time PCR has been MDRTB detection. two Interleukins measurement serum using ELISA technique. Out individuals, there were 20 15 Serum IL18 IL22 levels significantly elevated (P<0.05) groups as compared control subjects. group showed higher than group. This study that had relationship might be used help diagnose TB; Clinical diagnosis may aided these tests.